63 lines
977 B
Modula-2
63 lines
977 B
Modula-2
:Comment : L6
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:Reference : : Adams et al. 1982 - M-currents and other potassium currents in bullfrog sympathetic neurones
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:Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21
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: **Modified to use 'celsius' for temperature to correct rates by Aman Aberra**
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NEURON {
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SUFFIX Im
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USEION k READ ek WRITE ik
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RANGE gImbar, gIm, ik, celsius
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}
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UNITS {
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(S) = (siemens)
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(mV) = (millivolt)
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(mA) = (milliamp)
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}
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PARAMETER {
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gImbar = 0.001000 (S/cm2)
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celsius = 35
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}
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ASSIGNED {
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v (mV)
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ek (mV)
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ik (mA/cm2)
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gIm (S/cm2)
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mInf
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mTau
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mAlpha
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mBeta
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}
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STATE {
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m
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}
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BREAKPOINT {
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SOLVE states METHOD cnexp
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gIm = gImbar*m
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ik = gIm*(v-ek)
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}
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DERIVATIVE states {
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rates()
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m' = (mInf-m)/mTau
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}
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INITIAL{
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rates()
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m = mInf
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}
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PROCEDURE rates(){
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LOCAL qt
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qt = 2.3^((celsius-21)/10)
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UNITSOFF
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mAlpha = 3.3e-3*exp(2.5*0.04*(v - -35))
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mBeta = 3.3e-3*exp(-2.5*0.04*(v - -35))
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mInf = mAlpha/(mAlpha + mBeta)
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mTau = (1/(mAlpha + mBeta))/qt
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UNITSON
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}
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